MAOIs taken with pethidine are actually associated with significant CNS excitation or depression (such as hypertension or hypotension). Whilst this has not been documented with dihydrocodeine, it is possible that the same conversation may perhaps take place and for that reason using dihydrocodeine needs to be avoided while the patient is taking MAOIs and for two months immediately after MAOI discontinuation.
Persist with very simple foods - stay clear of rich or spicy foods. Take your doses immediately after foods, as this will likely assistance guard your stomach
If you can get any Unintended effects, check with your health practitioner, pharmacist or nurse. This involves any attainable side effects not outlined During this leaflet.
Using dihydrocodeine (DHC) consistently for a long time can cause addiction, which might result in you to definitely feel restless and irritable if you cease the tablets
Administration to nursing women isn't advisable as codeine might be secreted in breast milk and may lead to respiratory depression during the infant.
Nonetheless it is assumed to affect the discharge of various neurotransmitters from afferent nerves delicate to unpleasant stimuli and maybe partially answerable for the analgesic influence.
• taking dihydrocodeine consistently for many years can guide to dependancy, which could lead to you to definitely here truly feel restless and irritable whenever you end the tablets
Immediately after oral administration the bioavailability in the drug is about 20%, indicating the pre-systemic metabolism performs a considerable purpose in decreasing the get more info bioavailability of dihydrocodeine.
You should normally take the drug as prescribed by your medical professional and hardly ever exceed the said dose. It is also not a smart idea to blend it with Alcoholic beverages as you could possibly come across the consequences with the Liquor intensified.
Minimising pain is useful for Restoration. For anyone who is cellular then your risk of the article-operative blood clot are going to be lowered. You may also manage to cough a lot more easily to avoid a chest infection soon after an Procedure.
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Always choose Dihydrocodeine exactly as your medical doctor has instructed you. You must check with your medical professional or pharmacist if You're not guaranteed.
Frequent prolonged use of DHC is understood to bring on dependancy and tolerance. Signs of restlessness and irritability may possibly end result when therapy is then stopped.